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Effects of the Kappa-opioid Receptor Agonist, U69593, on the Development of Sensitization and on the Maintenance of Cocaine Self-administration

✍ Scribed by Susan Schenk; Brian Partridge; Toni S Shippenberg


Book ID
114280719
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
432 KB
Volume
24
Category
Article
ISSN
1470-634X

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Repeated administration of the selective
✍ JosΓ© Antonio Fuentealba; Katia Gysling; Karin Magendzo; MarΓ­a Estela AndrΓ©s πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 244 KB

Reinforcing properties of drugs of abuse are reduced by the coadministration of kappa opioid receptor (KOR) agonists. This effect is related to the inhibition of dopamine (DA) release in the nucleus accumbens (NAc) produced by the acute administration of KOR agonists. The present study was undertake