Effects of the herbicide prometryn on the physicochemical properties of artificial model membranes

✍ Scribed by Bertoluzza, A; Bonora, S; Fini, G; Morelli, M A

• Publisher: John Wiley and Sons
• Year: 1999
• Tongue: English
• Weight: 146 KB
• Volume: 55
• Category: Article
• ISSN: 1526-498X
• DOI: 10.1002/(sici)1096-9063(199902)55:2<147::aid-ps864>3.0.co;2-f

✦ Synopsis

Several derivatives of 1,3,5-triazine (eg atrazine, prometryn) are eþ ective herbicides and have been extensively used in agriculture. A study of prometryn (Prom)-phospholipid (PL), with different charges, was carried out by means of calorimetric and spectroscopic techniques. The Promdipalmitoylphosphatidylcholine (DPPC) and Prom-dipalmitoylphosphatidic acid (DPPA) water suspensions systems at pH values ranging from 5 to 9 were investigated. The results show that Prom does not signiücantly perturb the hydrophobic core of the lipid bilayer and suggest that the herbicide localizes near the glycerol backbone of the lipid, perturbing the environment of the carbonyls of the two ester groups. At pH 5 the vibrational band attributable to N-H stretch of Prom disappears thus suggesting that the absorption into the bilayer modiües the physicochemical properties of the herbicide. The two PL considered behave similarly and the eþ ect of the charge is not noticeable. The strength of the Prom-PL interaction decreases with decreasing pH.