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Effects of the carcinogen dimethylhydrazine (DMH) on the function of rat colonic crypts

✍ Scribed by M. Bleich; D. Ecke; B. Schwartz; G. Fraser; R. Greger

Publisher
Springer
Year
1996
Tongue
English
Weight
223 KB
Volume
433
Category
Article
ISSN
0031-6768

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1,2-dimethylhydrazine (DMH)-induced colon cancer in Wistar/Furth (W/Fu) rats is analogous in many ways to human colorectal cancer. As part of our attempt to understand the immunobiology of these tumors, we have utilized the recently available monoclonal antibodies W3/25 and OX8 to monitor helper (Th