## Abstract The radioactivity level in blood, bile, urine and contents of parts of the gastroโintestinal tract in rats was studied after subcutaneous administration of ^3^Hโ1,2โdimethylhydrazine (^3^HโSDMH) which induces colonic tumours. The alkylation of DNA, RNA and protein in the intestinal muco
Effect of the enterotropic carcinogen 1,2-dimethylhydrazine on the hypothalamic biogenic amine level in rats
โ Scribed by V. N. Anisimov; V. K. Pozdeev; A. Yu. Dmitrievskaya; G. M. Gracheva; A. P. Il'in; V. M. Dil'man
- Publisher
- Springer US
- Year
- 1976
- Tongue
- English
- Weight
- 273 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0007-4888
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Pyrroxan (20 mg/kg, i.p.) , a new potential antianxiety agent, increased brain norepinephrine (NE) turnover in rats, reflecting a possible central e-adrenergic receptor blocking activity, in contrast, chlordiazepoxide (20 mg/kg, i.p.), a widely used antianxiety agent, did not alter the NE turnover.
1,2-dimethylhydrazine (DMH)-induced colon cancer in Wistar/Furth (W/Fu) rats is analogous in many ways to human colorectal cancer. As part of our attempt to understand the immunobiology of these tumors, we have utilized the recently available monoclonal antibodies W3/25 and OX8 to monitor helper (Th
## Abstract 1,2โdimethylhydrazine (DMH), administered weekly to mice for 20 weeks, induces tumors in the distal segment of colon. Tumors are preceded by enlargement of the mucosal glands resulting from increases in the number of total cells and ^3^Hโthymidine labeled cells/crypt. Cells located in t