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Effects of tamoxifen and octreotide LAR on the IGF-system compared with tamoxifen monotherapy

✍ Scribed by S.I. Helle; W. Mietlowski; J.P. Guastalla; I. Szakolczai; E. Bajetta; H. Sommer; E. Baltali; T. Pinter; M. Csepreghy; L. Ottestad; C. Boni; C. Bryce; J.G.M. Klijn; P.E. Lønning

Book ID
116428453
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
143 KB
Volume
41
Category
Article
ISSN
0959-8049

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Plasma levels of IGF-I, IGFBP-I and IGFBP-3 were measured before and during treatment with tamoxifen up to 19+ months in 34 post-menopausal patients with advanced breast cancer. In 28 patients, pro-IGF-IIE (IGF-IIE) levels were determined and IGFBP-3 was evaluated by immunoblot in 27 patients. Tamox