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Effects of SQ 27,427, a thromboxane A2 receptor antagonist, in the human platelet and isolated smooth muscle

✍ Scribed by Don N. Harris; Roland Greenberg; Marie B. Phillips; Inge M. Michel; Harold J. Goldenberg; Martin F. Haslanger; Thomas E. Steinbacher


Book ID
115878394
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
668 KB
Volume
103
Category
Article
ISSN
0014-2999

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Picotamide (G 137), a new non prostanoid inhibitor of in vitro arachidonic acid induced platelet aggregation, has been further characterized in in vitro and ex vivo studies. When whole blood was activated with collagen in the presence of picotamide 5 x 10(-4) M, thromboxane B2 production was decreas