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Combined administration of 5-HT2 and thromboxane A2 antagonists: effects on platelet aggregation and isolated cardiac muscle

✍ Scribed by Linda A Shaw; Andrew J Batey; Susan J Coker


Book ID
110002996
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
407 KB
Volume
121
Category
Article
ISSN
0007-1188

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Picotamide (G 137), a new non prostanoid inhibitor of in vitro arachidonic acid induced platelet aggregation, has been further characterized in in vitro and ex vivo studies. When whole blood was activated with collagen in the presence of picotamide 5 x 10(-4) M, thromboxane B2 production was decreas