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Effects of solutes on solubilization and refolding of proteins from inclusion bodies with high hydrostatic pressure

✍ Scribed by Seung-Hyun Lee; John F. Carpenter; Byeong S. Chang; Theodore W. Randolph; Yong-Sung Kim


Book ID
111752625
Publisher
Cold Spring Harbor Laboratory Press
Year
2006
Tongue
English
Weight
344 KB
Volume
15
Category
Article
ISSN
0961-8368

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## Abstract The application of high hydrostatic pressure is an effective tool to promote dissolution and refolding of protein from aggregates and inclusion bodies while minimizing reaggregation. In this study we explored the mechanism of high‐pressure protein refolding by quantitatively assessing t