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Effects of solute–matrix interaction on monitoring the conformational changes of immobilized proteins by surface plasmon resonance sensor

✍ Scribed by Liang-Yu Chen; Ming-Chia Wu; Mao-Tsun Chou; Li-An Kao; Shean-Jen Chen; Wen-Yih Chen


Book ID
116901224
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
294 KB
Volume
67
Category
Article
ISSN
0039-9140

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Behaviors of proteins immobilized on a solid surface were investigated using BIACORE, a biosensor utilizing surface plasmon resonance. This sensor is usually used for analyzing binding events during biomolecular interactions. Here we propose a novel use of this sensor to monitor two kinds of intramo