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Effects of scoparone on dopamine release in PC12 cells

✍ Scribed by Yoo Jung Yang; Hak Ju Lee; Byung Koo Lee; Sung Cil Lim; Chong Kil Lee; Myung Koo Lee


Book ID
113624094
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
538 KB
Volume
81
Category
Article
ISSN
0367-326X

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## Abstract The effects of scoparone on dopamine biosynthesis and L‐DOPA‐induced cytotoxicity in PC12 cells were investigated. PC12 cells treated with scoparone at concentrations of 100–200 ΞΌM showed a 128–136% increase in dopamine levels over the course of 24 hr. Scoparone significantly increased