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Effects of iptakalim on rotenone-induced cytotoxicity and dopamine release from PC12 cells

✍ Scribed by Yong Yang; Xing Liu; Jian-Hua Ding; Jing Sun; Yan Long; Fang Wang; Hong-Hong Yao; Gang Hu

Book ID
116766796
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
192 KB
Volume
366
Category
Article
ISSN
0304-3940

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## Abstract The effects of scoparone on dopamine biosynthesis and L‐DOPA‐induced cytotoxicity in PC12 cells were investigated. PC12 cells treated with scoparone at concentrations of 100–200 ΞΌM showed a 128–136% increase in dopamine levels over the course of 24 hr. Scoparone significantly increased