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Effects of RNA Interference on CD80 and CD86 Expression in Bone Marrow-derived Murine Dendritic Cells

โœ Scribed by X. Gu; J. Xiang; Y. Yao; Z. Chen


Book ID
110861373
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
177 KB
Volume
64
Category
Article
ISSN
0300-9475

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The interaction of CD28 and its ligands (CD80, CD86) on antigen presenting cells and that of TCR/CD3-MHC are required for T lymphocyte activation. To determine whether impaired lymphocyte proliferation associated with iron deficiency is due to reduced expression of these ligands, spleen cells obtain