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Effects of repeated brief episodes of ischemia and reperfusion in isolated perfused rat hearts

✍ Scribed by Toshiaki Yasumura; Nobuo Aoki; Atsuo Yanagisawa; Akira Maki; Chiaki Shirato; Kyozo Ishikawa

Publisher
Springer
Year
1999
Tongue
English
Weight
648 KB
Volume
14
Category
Article
ISSN
0910-8327

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πŸ“œ SIMILAR VOLUMES

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Free radical species have been implicated as important agents involved in myocardial ischemie and reperfusion injuries. In our study, formation of free radicals was measured directly with electron paramagnetic resonance spectroscopy before ischemia, during 10 minutes of global ischemia, and 20 secon

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## Abstract The objective of this study was to determine the effects of repetitive ischemia on myocardial oxygen tension (pO~2~), consumption, and delivery in crystalloid normoperfused (perfu‐sion pressure > 70 mmHg) and hypoperfused (perfusion pressure ˜50 mmHg) constant flow isolated rat hearts.

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## Abstract The effect of ischemia and reperfusion on transverse relax ation (__T__~2~) of intracellular Na^+^ (Na^+^~i~) was measured with 5‐min time resolution in isolated rat hearts. Na~i~ __T__~2~ relaxation was biexponential with 28 Β± 7% fast (T~2f~)and 72 Β± 7% slow (__T__~2s~) decay. This rat