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Effects of regulatory domains of specific isoforms of protein kinase C on growth control and apoptosis in MCF-7 breast cancer cells

✍ Scribed by Jae-Won Soh; Yun-Sil Lee; I. Bernard Weinstein


Book ID
114424736
Publisher
Wiley (Blackwell Publishing)
Year
2003
Tongue
English
Weight
499 KB
Volume
3
Category
Article
ISSN
1533-869X

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Tamoxifen, a synthetic antiestrogen, is known for its antitumoral action in vivo; however, it is well accepted that many tamoxifen effects are elicited via estrogen receptor-independent routes. Previously, we reported that tamoxifen induces PKC translocation in fibroblasts. In the present study, we