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Comparative effects of 1,25(OH)2D3and EB1089 on cell cycle kinetics and apoptosis in MCF-7 breast cancer cells

✍ Scribed by Maura Simboli-Campbell; Carmen J. Narvaez; Kathryn VanWeelden; Martin Tenniswood; JoEllen Welsh


Book ID
110229093
Publisher
Springer US
Year
1997
Tongue
English
Weight
253 KB
Volume
42
Category
Article
ISSN
0167-6806

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## Abstract 1Ξ±,25‐Dihydroxyvitamin D~3~ [1Ξ±,25(OH)~2~D~3~], the hormonally active form of vitamin D~3~, has been shown to be a potent negative growth regulator of breast cancer cells both in vitro and in vivo. 1Ξ±,25(OH)~2~D~3~ acts through two different mechanisms. In addition to regulating gene tr