𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Effects of radiotherapy with or without chemotherapy on tongue strength and swallowing in patients with oral cancer

✍ Scribed by Cathy Lazarus; Jeri A. Logemann; Barbara Roa Pauloski; Alfred W. Rademaker; Irene B. Helenowski; Edward F. Vonesh; Ellen MacCracken; Bharat B. Mittal; Everett E. Vokes; Daniel J. Haraf

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
118 KB
Volume
29
Category
Article
ISSN
1043-3074

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Background.

Oral tongue strength and swallowing ability are reduced in patients treated with chemoradiotherapy for oral and oropharyngeal cancer.

Methods.

Patients with oral or oropharyngeal cancer treated with high‐dose chemoradiotherapy underwent tongue strength, swallowing, and dietary assessments at pretreatment and 1, 3, 6, and 12 months posttreatment. Tongue strength was assessed using the Iowa Oral Performance Instrument (IOPI). Oral and pharyngeal residue was evaluated utilizing videofluoroscopy.

Results.

Mean maximum tongue strength dropped a nonsignificant amount immediately after treatment, and then increased significantly at 6‐ and 12‐months posttreatment completion. Analyses were adjusted for patient dropout. Tongue strength was not significantly correlated with swallow observations of percentage oral and pharyngeal residue. Ability to eat various diet consistencies was reduced after treatment but improved over time at a rate similar to changes in oral intake and type of diet.

Conclusions.

Parallel but not significant changes in oral intake, diet, and tongue strength in the first year post chemoradiation therapy need further study in a larger population. © 2007 Wiley Periodicals, Inc. Head Neck, 2007

📜 SIMILAR VOLUMES

Effect of induction chemotherapy on spee
Effect of induction chemotherapy on speech and swallowing function in patients with oral tongue cancer
✍ Denise A. Barringer; Katherine A. Hutcheson; Erich M. Sturgis; Merrill S. Kies; 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 196 KB 👁 2 views

## Abstract ## Background. Swallowing physiology, diet, and patient‐reported outcomes were evaluated after induction chemotherapy for oral tongue cancer. ## Methods. Fifteen of 23 patients enrolled in a phase II clinical trial of induction chemotherapy followed by surgical resection for oral ton

Relationship between swallow motility di
Relationship between swallow motility disorders on videofluorography and oral intake in patients treated for head and neck cancer with radiotherapy with or without chemotherapy
✍ Barbara Roa Pauloski; Alfred W. Rademaker; Jerilyn A. Logemann; Lisa Newman; Ell 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 157 KB 👁 1 views

## Background: Current research demonstrates that swallow function is impaired after treatment with organ-sparing chemoradiotherapy. few studies, however, have related observed swallowing disorders with the patient's oral intake and diet in a large cohort of patients. ## Methods: Swallowing funct

Patient-reported measurements of oral mu
Patient-reported measurements of oral mucositis in head and neck cancer patients treated with radiotherapy with or without chemotherapy : Demonstration of increased frequency, severity, resistance to palliation, and impact on quality of life
✍ Linda S. Elting; Dorothy M. Keefe; Stephen T. Sonis; Adam S. Garden; F. K. L. Sp 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 358 KB 👁 2 views

## Abstract ## BACKGROUND. The risk, severity, and patient‐reported outcomes of radiation‐induced mucositis among head and neck cancer patients were prospectively estimated. ## METHODS. A validated, patient‐reported questionnaire (OMDQ), the FACT quality of life (QOL), and the Functional Assessm

Quality of life in patients with orophar
Quality of life in patients with oropharynx carcinomas: Assessment after accelerated radiotherapy with or without chemotherapy versus radical surgery and postoperative radiotherapy
✍ Abdelkarim S. Allal; Kevin Nicoucar; Nicolas Mach; Pavel Dulguerov 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 97 KB 👁 1 views

## Abstract ## Background. In oropharyngeal carcinomas, it is assumed that the effectiveness of the different treatment approaches is roughly equivalent, whereas the functional outcome after radical radiotherapy (RT) is superior to that associated with primary surgery. The aim of this study is to

Survival benefits of adjuvant chemothera
Survival benefits of adjuvant chemotherapy with oral doxifluridine (5′-DFUR) following radiotherapy in patients with unresectable pancreatic cancer
✍ Koji Tsuruta; Astutake Okamoto; Naoto Egawa; Terumi Kamisawa; Katsuyuki Karasawa 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 126 KB

## Abstract ## Background and Objectives The combination of 5‐fluorouracil and radiotherapy is thought to be the most effective treatment for locally unresectable pancreatic carcinoma. The outcomes, however, are far from acceptable from the viewpoint of long‐term survival. We assessed the survival

Effects of oral UFT combined with or wit
Effects of oral UFT combined with or without zoledronic acid on bone metastasis in the 4T1/luc mouse breast cancer
✍ Toru Hiraga; Akimi Ueda; Daisuke Tamura; Kenji Hata; Fumiyo Ikeda; Paul J. Willi 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 French ⚖ 238 KB 👁 1 views

Bone metastasis is one of the major causes of increased morbidity and eventual mortality in breast cancer patients. Therefore, intervention of bone metastases is one of the important targets in the management of breast cancer. In the present study, we examined the effects of the orally administrable