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Effects of pyrrolidine dithiocarbamate on beta-amyloid (25–35)-induced inflammatory responses and memory deficits in the rat

✍ Scribed by Guanliang Cheng; Shawn N. Whitehead; Vladimir Hachinski; David F. Cechetto


Book ID
113811999
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
861 KB
Volume
23
Category
Article
ISSN
0969-9961

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## Abstract Male Wistar rats received unilateral intrahippocampal injections of 3 nmol (3.18 μg) aggregated Aβ(25–35), intracerebroventricular bilateral injections of 0.5 μg human recombinant TNFα or both (Aβ(25–35) + TNFα‐treated animals). Seven days after the surgery brain sections were stained w