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Differential effects of tumor necrosis factor-alpha co-administered with amyloid beta-peptide (25–35) on memory function and hippocampal damage in rat

✍ Scribed by Mikhail Stepanichev; Irina Zdobnova; Irina Zarubenko; Natalia Lazareva; Natalia V. Gulyaeva


Book ID
116284433
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
940 KB
Volume
175
Category
Article
ISSN
0166-4328

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## Abstract Male Wistar rats received unilateral intrahippocampal injections of 3 nmol (3.18 μg) aggregated Aβ(25–35), intracerebroventricular bilateral injections of 0.5 μg human recombinant TNFα or both (Aβ(25–35) + TNFα‐treated animals). Seven days after the surgery brain sections were stained w