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Effects of prostaglandin E2 on gene expression in primary osteoblastic cells from prostaglandin receptor knockout mice

โœ Scribed by X Li; C.C Pilbeam; L Pan; R.M Breyer; L.G Raisz


Book ID
117807605
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
393 KB
Volume
30
Category
Article
ISSN
8756-3282

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โœ Haruhiko Tokuda; Jun Kotoyori; Atsushi Suzuki; Yutaka Oiso; Osamu Kozawa ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 602 KB

We investigated the effects of vitamin D3 on the signaling pathways by prostaglandin E, (PGE2) in osteoblast-like MC3T3-El cells. The pretreatment with 1,25-dihydroxyvitamin D3 (1 ,25-(OH),D3), an active form of vitamin D3, significantly inhibited cAMP accumulation induced by 10 (LM PGE, in a dose-d