Effects of vitamin D3 on signaling by pr
โ
Haruhiko Tokuda; Jun Kotoyori; Atsushi Suzuki; Yutaka Oiso; Osamu Kozawa
๐
Article
๐
1993
๐
John Wiley and Sons
๐
English
โ 602 KB
We investigated the effects of vitamin D3 on the signaling pathways by prostaglandin E, (PGE2) in osteoblast-like MC3T3-El cells. The pretreatment with 1,25-dihydroxyvitamin D3 (1 ,25-(OH),D3), an active form of vitamin D3, significantly inhibited cAMP accumulation induced by 10 (LM PGE, in a dose-d