𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Effects of preservation and sterilization on cortical bone grafts

✍ Scribed by G. Voggenreiter; R. Ascherl; G. Blümel; K. P. Schmit-Neuerburg

Publisher
Springer
Year
1994
Tongue
English
Weight
364 KB
Volume
113
Category
Article
ISSN
1434-3916

No coin nor oath required. For personal study only.

✦ Synopsis

The effects of preservation and sterilization on the structural properties of cortical bone were investigated. Specimens of cortical bone from rat tibiae were frozen (-70°C for 28 days), freeze-dried, irradiated (1, 5, 25 and 50 kGy) or autoclaved (at 134°C for 3 or 5 rain), and examined by scanning electron microscopy. Cryopreservation and irradiation had no deleterious effects on the surface structure of the cortical bone. Freeze-drying caused microcracks running parallel to the mineralized fiber bundles. After autoclaving, a time-dependent distension, swelling and amalgamation of the fibrillary matrix was observed. This denaturation of the organic matrix was more pronounced after 5 min than 3 min autoclaving. The alterations of the fibrillary structure described above might be due to a preservation-and sterilization-induced decrease of the biological and biomechanical potential of bone grafts.

📜 SIMILAR VOLUMES

The effects of cisplatin on the incorpor
The effects of cisplatin on the incorporation of fresh syngeneic and frozen allogeneic cortical bone grafts
✍ David J. Zart; Leslie Miya; David A. Wolff; John T. Makley; Dr. Sharon Stevenson 📂 Article 📅 1993 🏛 Elsevier Science 🌐 English ⚖ 955 KB

## Abstract Allograft transplantation with concomitant chemotherapy has proven successful in the treatment of malignant bone tumors. However, these chemotherapeutic agents may delay tissue healing, resulting in clinical complications. To clarify the effects of cisplatin on the healing of bone graft

Effect of sterilization on bone morphoge
Effect of sterilization on bone morphogenetic protein
✍ Dr. Shinichiro Ijiri; Takao Yamamuro; Takashi Nakamura; Seiya Kotani; Kouchei No 📂 Article 📅 1994 🏛 Elsevier Science 🌐 English ⚖ 818 KB

## Abstract Demineralized bone matrix and bone morphogenetic protein have been used clinically to accelerate bone regeneration. However, the best method of sterilization has been the subject of controversy. Some investigators have used ethylene oxide, but others have reported that doses adequate fo

Effects of CO2 laser beam on cortical bo
Effects of CO2 laser beam on cortical bone
✍ Ghazi M. Rayan; Jan V. Pitha; Janet S. Edwards; Royce B. Everett 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 437 KB

Sixteen bone blocks from two freshly amputated legs were used to study the effect of CO2 laser on cortical bone. They were divided into two groups. In Group I, the blocks were treated with CO2 laser using 1 mm spot (focused mode). In Group II, they were treated with CO2 laser using 3 mm spot (defocu