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Effects of Preactivated Autologous T Lymphocytes on CD80, CD86 and CD95 Expression by Chronic Lymphocytic Leukemia B Cells

✍ Scribed by Romano, Ciro; De Fanis, Umberto; Sellitto, Ausilia; Dalla Mora, Liliana; Chiurazzi, Federico; Giunta, Riccardo; Rotoli, Bruno; Lucivero, Giacomo

Book ID: 121395305
Publisher: Informa plc
Year: 2003
Tongue: English
Weight: 256 KB
Volume: 44
Category: Article
ISSN: 1042-8194
DOI: 10.1080/1042819031000111026

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## Abstract To develop an effective antitumor immunotherapy for B‐lineage non‐Hodgkin's lymphoma, we constructed a tetravalent tandem diabody (tanDb) specific for both human CD19 (B‐cell marker) and CD3 (T‐cell antigen). Here, we report the effective killing of malignant primary B cells from patien