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Effects of polyamines and methylglyoxal bis(guanylhydrazone) on Escherichia coli ribonucleic acid polymerase and the template activity of hepatic cell nuclei in vitro

✍ Scribed by Norman F. Nelson; K.Birgitta Brown; Bruce R. Fehlman; Gregory P. Stewart; David G. Brown


Book ID
115747006
Publisher
Elsevier Science
Year
1978
Weight
592 KB
Volume
517
Category
Article
ISSN
0005-2787

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## Abstract The effect of oxidation of the methionine residues of __Escherichia coli__‐derived recombinant human stem cell factor (huSCF) to methionine sulfoxide on the structure and activity of SCF was examined. Oxidation was performed using hydrogen peroxide under acidic conditions (pH 5.0). The