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Effects of Pluronic F68 and Labrasol on the intestinal absorption and pharmacokinetics of rifampicin in rats

✍ Scribed by Li Ma; Yuhui Wei; Yan Zhou; Xiaohua Ma; Xin’an Wu

Book ID
107642584
Publisher
Springer
Year
2011
Tongue
English
Weight
216 KB
Volume
34
Category
Article
ISSN
0253-6269

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Tuberculosis chemotherapy involves combination of the drugs isoniazid (INH), rifampicin (RMP) and pyrazinamide (PYR) for a 6-month period. The present work investigated the influence of RMP and PYR on the pharmacokinetic parameters of INH when groups of rats were pre-treated for 21 days with INH alo