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Effects of PDGF and IGF-I on chondrocyte proliferation and differentiation

✍ Scribed by WROBLEWSKI, J; EDWALL, C

Book ID: 122263930
Publisher: Elsevier Science
Year: 1990
Tongue: English
Weight: 135 KB
Volume: 14
Category: Article
ISSN: 0309-1651
DOI: 10.1016/0309-1651(90)90485-H

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## Abstract Insulin‐like growth factor (IGF)‐I stimulates both proliferation and differentiation of myogenic precursor cells. In vivo, IGFs are bound to one of the members of a family of six high‐affinity IGF binding proteins (IGFBP 1–6) that regulate their biological activity. One of these binding