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Effects of intermittent versus continuous parathyroid hormone administration on condylar chondrocyte proliferation and differentiation

✍ Scribed by Qi Liu; Qilong Wan; Rongtao Yang; Haihua Zhou; Zubing Li


Book ID
116303669
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
705 KB
Volume
424
Category
Article
ISSN
0006-291X

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Parathyroid hormone (PTH) binds specifically to the hypertrophic region of growth plate cartilage [16]. This specific binding suggests a role for this hormone in chondrocyte maturation. Enzymatically isolated chick articular and growth plate chondrocytes grown in monolayer culture were used to assay

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## Abstract ## Objective To investigate the effect of intermittent administration of human parathyroid hormone (PTH) on bone mineral density (BMD) and arthritis in rats with collagen‐induced arthritis (CIA). ## Methods Seven‐month‐old female Sprague‐Dawley rats were divided into 4 groups: rats w