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Effects of paternal folate deficiency on the expression of insulin-like growth factor-2 and global DNA methylation in the fetal brain

✍ Scribed by Kim, Hye Won; Kim, Ki Nam; Choi, Yun Jung; Chang, Namsoo


Book ID
120567464
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
526 KB
Volume
57
Category
Article
ISSN
1613-4125

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## Abstract The use of surrogate end‐point biomarkers could help in the development of chemopreventive agents. To define potential surrogate end‐point biomarkers, the ability of budesonide to decrease mRNA expression of the insulin‐like growth factor‐2 (__Igf‐II__) and c‐__myc__ genes and to cause