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Effects of ORG 30029, dobutamine, and high perfusate calcium on function and metabolism in rat heart

โœ Scribed by Grandis, D.J.; MacGowan, G.A.; Koretsky, A.P.

Book ID
122401169
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
153 KB
Volume
31
Category
Article
ISSN
1558-3597

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## Background: In perfused hearts, high calcium-induced inotropy results in less developed pressure relative to myocardial oxygen consumption compared to the ฮฒ-adrenergic agonist dobutamine. Calcium handling is an important determinant of myocardial oxygen consumption. Therefore, we hypothesized t