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Effects of oligonucleotide adsorption on the physicochemical characteristics of a nanoparticle-based model delivery system for antisense drugs

✍ Scribed by Götting, N.; Fritz, H.; Maier, M.; von Stamm, J.; Schoofs, T.; Bayer, E.


Book ID
113039364
Publisher
Springer
Year
1999
Weight
283 KB
Volume
277
Category
Article
ISSN
0340-255X

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## Abstract A set of four 9‐mer oligonucleotide duplexes formed between the 5′‐GCAT__N__TCAC‐3β€², __N__=A,C,T,G, and the 5′‐GTGATATGC‐3β€² complement has been proposed as a model system for the investigation of novel oligonucleotide analogues (candidates for antisense use) binding selectivity. Raman m