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Effects of nordihydroguaiuretic acid on sulfidopeptide leukotriene activity and hypoxic pulmonary vasoconstriction in the isolated sheep lung

✍ Scribed by J. Schnader; B. Undem; S.P. Peters; J.T. Sylvester

Book ID
119051486
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
762 KB
Volume
46
Category
Article
ISSN
0090-6980

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In the rat pulmonary vasculature perfused with blood in situ vasoconstriction induced by hypoxia was reversed by isoprenaline (doses greater than 1 ng) and adrenaline (doses greater than 30 ng) and exacerbated by phenylephrine but not UK 14304. Doses of adrenaline less than 30 ng had no effect, exce