Effects of nerve stimulation on spontaneously active preparations of the guinea pig ureter
โ Scribed by Exintaris, B. ;Lang, R. J.
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 174 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0300-5623
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The effects of nerve stimulation on the electrical and mechanical activity of the smooth muscle of the proximal renal pelvis of the guinea-pig were investigated using standard tension and microelectrode recording techniques. Spontaneous action potentials were deemed to have been recorded from three
Low calcium concentration in the external medium depolarises the membrane of smooth muscle cells of the ureter and their excitability diminishes. The Ca++ dependent oscillations of the action potential disappears, while the plateau component is more resistent. Analogous reactions are observed by the
Increase of the external K+ concentration depolarises the ureteral muscle membrane and induces, after a transient period of increased spontaneous activity, a tonic contraction. Tetraethylammonium, in concentrations normally required for ganglion blocking activity, does not influence the ureteral act