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Effects of N-acetyl-l-cysteine and ascorbic acid on mutagen-induced chromosomal sensitivity in patients with head and neck cancers

✍ Scribed by Zoltan Trizna; Stimson P. Schantz; T.C. Hsu


Book ID
115695233
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
599 KB
Volume
162
Category
Article
ISSN
0002-9610

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## Abstract Arsenic trioxide (ATO) has been recommended for the treatment of refractory cases of acute promyelocytic leukemia (APL). Recent studies in our laboratory indicated that oxidative stress plays a key role in ATO‐induced cytotoxicity in human leukemia (HL‐60) cells. In the present investig