The effect of N-acetyl-l-cysteine and ascorbic acid on visible-light-irradiated camphorquinone/N,N-dimethyl-p-toluidine-induced oxidative stress in two immortalized cell lines

Differential effect of ascorbic acid and

Differential effect of ascorbic acid and n-acetyl-l-cysteine on arsenic trioxide-mediated oxidative stress in human leukemia (HL-60) Cells

✍ Clement G. Yedjou; Christian Rogers; Erika Brown; Paul B. Tchounwou 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 233 KB 👁 1 views

## Abstract Arsenic trioxide (ATO) has been recommended for the treatment of refractory cases of acute promyelocytic leukemia (APL). Recent studies in our laboratory indicated that oxidative stress plays a key role in ATO‐induced cytotoxicity in human leukemia (HL‐60) cells. In the present investig