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Effects of morphine andd-Ala2-d-Leu5-enkephalin in the seizure-susceptible El mouse

โœ Scribed by Seiji Koide; Hiroshi Onishi; Sakae Yamagami; Yukio Kawakita

Publisher
Springer
Year
1992
Tongue
English
Weight
396 KB
Volume
17
Category
Article
ISSN
0364-3190

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Synthesis of [D-Ala2, D-Leu5]enkephalin
Synthesis of [D-Ala2, D-Leu5]enkephalin tritiated in the 2,6-positions of tyrosine
โœ Hiroshi Hasegawa; Yoshihiko Shinohara; Shigeo Baba ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 351 KB

D-Ma2, D-Leu51Enkephalin (DADLE) labelled with tritium in the 2,6-positions of N-terminus tyrosine residue has been prepared. Synthesis of the precursor peptide, [2,6-dibromo-Tyrl]DADLE, was performed by solid phase synthesis using F'moc strategy. The peptide was tritiated catalytically to yield [2