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Effects of mitomycin C on sister chromatid exchange in normal and bloom's syndrome cells

✍ Scribed by Yukimasa Shiraishi; Avery A. Sandberg


Book ID
113191392
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
362 KB
Volume
49
Category
Article
ISSN
0027-5107

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πŸ“œ SIMILAR VOLUMES


Implications of somatic recombination an
✍ David E. Comings πŸ“‚ Article πŸ“… 1975 πŸ› Springer 🌐 English βš– 397 KB

It is suggested that the somatic recombination observed in Bloom's syndrome and cells treated with mitomycin C may be the result of selection for recombination events that can occur only between homologous segments of DNA, rather than a result of somatic pairing in the nucleus.

Sister chromatid exchange and cell cycle
✍ S. Ved Brat πŸ“‚ Article πŸ“… 1979 πŸ› Springer 🌐 English βš– 656 KB

Sister chromatid exchange (SCE) has been studied in the fibroblasts of five Bloom's syndrome patients, one heterozygote, and two normal individuals. The high frequency of SCE already known in the lymphocytes of Bloom's syndrome was also found in the fibroblasts of all five patients. However, populat

Frequency of sister chromatid exchanges
✍ C. R. Bartram; H. W. RΓΌdiger; E. Passarge πŸ“‚ Article πŸ“… 1979 πŸ› Springer 🌐 English βš– 226 KB

Cocultivation of fibroblast cells from a male patient with Bloom syndrome (BS) and a female control reduced the rate of sister chromatid exchanges in the BS cells from a mean of 54 SCE per metaphase (range 42--65) to 41 (range 24--59). Medium used to culture control cells for 48 h also reduced the r

Cell cycle rate and sister chromatid exc
✍ R. Bamezai; Y. Shiraishi πŸ“‚ Article πŸ“… 1987 πŸ› Springer 🌐 English βš– 257 KB

A delay in cell cycle progression and a decrease in sister chromatid exchange (SCE) frequency was observed in Bloom syndrome (BS) cells when exposed to polyethylene glycol (PEG) treatment followed by co-cultivation with unexposed normal cells, whereas the SCE rate of both normal and BS cells increas