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Effects of mitogenic stimulation on the exchangeable pool of calcium in 3T3-cells

โœ Scribed by ENGSTROM, W; ROSENQVIST, U

Book ID
122313322
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
482 KB
Volume
5
Category
Article
ISSN
0309-1651

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The effect of time-controlled exposures to cholera toxin (CT) on intracellular levels of cyclic AMP (CAMP) and on the proliferative response of serumstimulated 3T3 cells was investigated. Continuous exposure to CT caused up to 8-fold raises in cAMP content and inhibited DNA replication by delaying G