𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Effects of mirtazapine in patients with post-traumatic stress disorder in Korea: a pilot study

✍ Scribed by Won-Myong Bahk; Chi-Un Pae; Joshua Tsoh; Jeong-Ho Chae; Tae-Youn Jun; Chul-Lee; Kwang-Soo Kim

Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
54 KB
Volume
17
Category
Article
ISSN
0885-6222

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

This study was aimed at testing the efficacy and tolerability of mirtazapine in the treatment of Korean patients with chronic post‐traumatic stress disorder (PTSD). Mirtazapine was administered for 8 weeks using a flexible‐dose regime in 15 Korean patients with PTSD based on the DSM‐IV criteria. We evaluated the patients at baseline and at weeks 4 and 8 after treatment with the interviewer‐administered structured interview for PTSD (SIP), short PTSD rating interview (SPRINT), impact of event scale‐revised (IES‐R) and the Montgomery Åsberg depression rating scale (MADRS). Scores on the SIP, SPRINT, IES‐R and MADRS had significantly reduced after 8 weeks treatment. In this pilot study, mirtazapine was found to be effective and well tolerated in the treatment of patients with PTSD. This calls for further evaluation of the effect of this drug on subjects with PTSD with randomized placebo‐controlled studies. Copyright © 2002 John Wiley & Sons, Ltd.

📜 SIMILAR VOLUMES

Procaine administration and behavioral r
Procaine administration and behavioral responsivity in post-traumatic stress disorder: a pilot study of tolerability
✍ Mark B. Hamner; Helen G. Ulmer; David F. Horne; Mark S. George; George W. Arana 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 126 KB 👁 2 views

Procaine, a local anesthetic, selectively activates the anterior limbic region of the brain, including the anterior cingulate, and may produce powerful emotional and other behavioral responses (including psychotic symptoms) in humans. In a pilot study, we administered intravenous procaine and placeb

Occurrence and treatment of post-traumat
Occurrence and treatment of post-traumatic stress disorder in an elderly patient after a traffic accident
✍ Markus Burgmer; Gereon Heuft 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 53 KB 👁 1 views

Post-traumatic stress disorder (PTSD) (American Psychiatric Association, 2000) describes the development of characteristic symptoms after a traumatic event in which the person involved (or those close to him) experience a threat to life or a threat to being injured (criterion A). Postulated are the

Bilateral hippocampal volume reduction i
Bilateral hippocampal volume reduction in adults with post-traumatic stress disorder: A meta-analysis of structural MRI studies
✍ Michael E. Smith 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 163 KB 👁 1 views

Over the last decade a significant number of studies have reported smaller hippocampal volume in individuals with symptoms of post-traumatic stress disorder (PTSD) relative to control groups, and in some cases hemispheric asymmetries in this effect have been noted. However these reported asymmetries

Effect of nizatidine on olanzapine-assoc
Effect of nizatidine on olanzapine-associated weight gain in schizophrenic patients in Korea: a pilot study
✍ Chi-Un Pae; Jung-Jin Kim; Kyung-Uk Lee; Chang-Uk Lee; Won-Myong Bahk; Soo-Jung L 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 49 KB

## Abstract A pilot study was conducted to evaluate the effect of nizatidine on olanzapine‐associated weight gain (OAWG) in ten patients with schizophrenia and schizophreniform disorder in Korea. Psychometric ratings with positive and negative syndrome scale (PANSS) and brief psychiatric rating sca

An unusual reaction to opioid blockade w
An unusual reaction to opioid blockade with naltrexone in a case of post-traumatic stress disorder
✍ Paloma Ibarra; Stephen P. Bruehl; Charles R. Carlson; John F. Wilson; Jane A. No 📂 Article 📅 1994 🏛 Springer 🌐 English ⚖ 385 KB

An unusual behavioral and cardiovascular reaction was observed during opioid blockade with naltrexone in a 32-year-old male who met DSM 111-R criteria f o r post-traumatic stress disorder (PTSD). As part of an ongoing placebo-controlled investigation of the effects of naltraone on laboratory and amb