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Effects of microwaves on membranes of hematopoietic cells in their structural and functional organization

✍ Scribed by Dr. Dolores Rotkovská; Alena Bartoničková; Jitka Kautská

Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
389 KB
Volume
14
Category
Article
ISSN
0197-8462

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✦ Synopsis

The role of cell membranes in stimulating and inhibiting the effects of microwaves was investigated in experiments carried out with a suspension of murine bone marrow cells irradiated with microwaves in vitro [f = 2.45 GHz, CW, specific absorption rate (SAR) = 12 W/kg]. Results obtained by means of a structural probe, 2.4-TNS, indicate that no structural changes occur in the region of the protein-lipid interphase under conditions of short-term irradiation with microwaves that induced temperatures in the range 36-45 "C (exposure time 315 and 525 s, respectively). Investigation of one functional parameter-the ability to produce hematopoietic colonies in the spleen after transplantation of the bone marrow irradiated in vitro by microwaves-indicated the possibility of affecting stirnulatory and inhibitory effects of microwaves by using a blocker of cell receptors, Trimepranol. The role of microwaves as a physical factor interfering in the process of cell proliferation at the level of receptor regulation is discussed.

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