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Effects of Methylglyoxal on Rat Pancreatic β-Cells

✍ Scribed by L.J Cook; J Davies; A.P Yates; A.C Elliott; J Lovell; J.A Joule; P Pemberton; P.J Thornalley; L Best

Book ID
119407521
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
506 KB
Volume
55
Category
Article
ISSN
0006-2952

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## Abstract Hyperlipidemia is frequently associated with insulin resistance states as found in type 2 diabetes and obesity. Effects of free fatty acids (FFA) on pancreatic β‐cells have long been recognized. Acute exposure of the pancreatic β‐cell to FFA results in an increase of insulin release, wh