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Effects of metformin on insulin resistance after injury in the rat

โœ Scribed by K. N. Frayn

Publisher
Springer
Year
1976
Tongue
English
Weight
813 KB
Volume
12
Category
Article
ISSN
0012-186X

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## Abstract It was reported that metformin was mainly metabolized via hepatic CYP2C11, 2D1 and 3A1/2 in rats, and in a rat model of dehydration, the expressions of hepatic CYP2C11 and 3A1/2 were not changed. Hence, it could be expected that the __Cl__~nr~ of metformin is comparable between two grou