## Abstract It was reported that metformin was mainly metabolized via hepatic CYP2C11, 2D1 and 3A1/2 in rats, and in a rat model of dehydration, the expressions of hepatic CYP2C11 and 3A1/2 were not changed. Hence, it could be expected that the __Cl__~nr~ of metformin is comparable between two grou
Effects of swimming on the pharmacokinetics and glucose tolerance of metformin in insulin-resistant rats
β Scribed by Kuei-Yu Chien; Ku-Fu Hsu; Hsin-I Lo; Ryh-Nan Pan; Chia-Hua Kuo; Fu-An Chen; Mei-Chich Hsu
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 102 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0142-2782
- DOI
- 10.1002/bdd.615
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract It was reported that the area under the plasma concentrationβtime curve from time zero to time infinity (AUC) of parathion was significantly smaller, and the timeβaveraged total body clearance (Cl) of parathion was significantly faster after intravenous administration of parathion to ra
Tuberculosis chemotherapy involves combination of the drugs isoniazid (INH), rifampicin (RMP) and pyrazinamide (PYR) for a 6-month period. The present work investigated the influence of RMP and PYR on the pharmacokinetic parameters of INH when groups of rats were pre-treated for 21 days with INH alo