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Effects of luteolin and quercetin, inhibitors of tyrosine kinase, on cell growth and metastasis-associated properties in A431 cells overexpressing epidermal growth factor receptor

✍ Scribed by Y -T Huang; J -J Hwang; P -P Lee; F -C Ke; J -H Huang; C -J Huang; C Kandaswami; E Middleton Jr; M -T Lee

Book ID
110004618
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
615 KB
Volume
128
Category
Article
ISSN
0007-1188

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The effect of tyrosine kinase inhibitor, erbstatin, on cell growth and mRNA expression of growth-factor/receptor system was examined in 6 human gastric-carcinoma cell lines. Erbstatin inhibited both EGF-induced and serum-stimulated cell growth of all 6 cell lines (TMK-I, MKN-I, -7, -28, -45, -74) in