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Effects of locus coeruleus lesions on morphine-induced antinociception

โœ Scribed by Donna L. Hammond; Herbert K. Proudfit

Book ID
118865856
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
791 KB
Volume
188
Category
Article
ISSN
0006-8993

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Previous studies have shown that the opioid antagonist naloxone does not alter neurotensin (NT)-induced antinociception. In the present studies, tolerance to morphine in mice significantly attenuated NT-induced antinociception, but not NT-induced hypothermia. In addition, centrally administered NT i