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Effects of lipids on bioavailability of sulfisoxazole acetyl, dicumarol, and griseofulvin in rats

โœ Scribed by Duane C. Bloedow; William L. Hayton

Publisher
John Wiley and Sons
Year
1976
Tongue
English
Weight
715 KB
Volume
65
Category
Article
ISSN
0022-3549

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Effect of serum protein binding on sulfi
Effect of serum protein binding on sulfisoxazole distribution, metabolism, and excretion in rats
โœ Avraham Yacobi; Gerhard Levy ๐Ÿ“‚ Article ๐Ÿ“… 1979 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 531 KB

This investigation determined the effect of serum protein binding on the kinetics of sulfisoxazole distribution, metabolism, and excretion. Adult rats, whose serum free fraction of sulfisoxazole (at a total concentration of 81 +/- 6 micrograms/ml) was 0.05-0.24, received a rapid intravenous injectio