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Effects of Kupffer cell-depletion on Concanavalin A-induced hepatitis

✍ Scribed by Masayo Hatano; Soichiro Sasaki; Shinsuke Ohata; Yoshiko Shiratsuchi; Takahiro Yamazaki; Kisaburo Nagata; Yoshiro Kobayashi

Book ID
113527100
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
927 KB
Volume
251
Category
Article
ISSN
0008-8749

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✍ Hiroyuki Nakashima; Manabu Kinoshita; Masahiro Nakashima; Yoshiko Habu; Satoshi πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 525 KB

Although concanavalin A (Con-A)-induced experimental hepatitis is thought to be induced by activated T cells, natural killer T (NKT) cells, and cytokines, precise mechanisms are still unknown. In the current study, we investigated the roles of Kupffer cells, NKT cells, FasL, tumor necrosis factor (T