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Effects of ketamine on metrazol-induced seizures during ontogenesis in rats

✍ Scribed by L. Velíšek; R. Mikolášová; S. Blanková-Vaňková; P. Mareš


Book ID
113223228
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
471 KB
Volume
32
Category
Article
ISSN
0091-3057

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Antimetrazol action of flunarizine (5, 10, 20 and 40 mg/kg i.p.) was tested during ontogenesis on male Wistar rats aged 7, 12, 18, 25 and 90 days. The latencies and incidences of jerks, minimal Metrazol seizures and major Metrazol seizures remained unchanged by flunarizine in all age groups. A speci