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Effect of anticonvulsants on seizures induced by kynurenine, quinolinic acid, strychnine, and metrazol

✍ Scribed by I. V. Ryzhov; I. P. Lapin


Publisher
Springer US
Year
1981
Tongue
English
Weight
353 KB
Volume
92
Category
Article
ISSN
0007-4888

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## Abstract Kainic acid (KA)‐induced status epilepticus (SE) is a well‐characterized model of excitotoxic neuronal injury. Excitotoxicity results from activation of specific glutamate receptors, with resultant elevation of intracellular Ca^2+^. The CA1 and CA3 subregions of the hippocampus are espe