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Effects of isofloxythepin enantiomers on prolactin secretion and postdecapitation convulsions in rats

โœ Scribed by Naohiro Matsuo; Katsushi Yamada; Shin-Ichiro Matsumoto; Mariko Domae; Koichi Shirakawa; Tatsuo Furukawa

Book ID
113221645
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
299 KB
Volume
30
Category
Article
ISSN
0091-3057

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Effect of flupenthixol and butaclamol is
Effect of flupenthixol and butaclamol isomers on prolactin secretion in rats
โœ Herbert Y. Meltzer; Steven M. Paul; Victor S. Fang ๐Ÿ“‚ Article ๐Ÿ“… 1977 ๐Ÿ› Springer ๐ŸŒ English โš– 283 KB

Cis (alpha)-flupenthixol and (+)-butaclamol are effective anti-psychotic agents but trans (beta)-flupenthixol and (-)-butaclamol are not. alpha-Flupenthixol was found to be 245 times more active in elevating rat plasma prolactin than the beta-isomer. The discrepancy between (+)-butaclamol and (-)-bu