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Effects of intracerebroventricular administration of pituitary adenylate cyclase-activating polypeptide (PACAP) on the motor activity and reserpine-induced hypothermia in murines

✍ Scribed by Yoshinori Masuo; Jiro Noguchi; Shigeru Morita; Yoshio Matsumoto

Book ID: 113127858
Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 721 KB
Volume: 700
Category: Article
ISSN: 0006-8993
DOI: 10.1016/0006-8993(95)00978-y

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The neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) is present in many regions of the adult and developing brain as are receptors for PACAP. PACAP stimulates different signalling cascades in neurons, involving cAMP, MAP kinase, and calcium. These characteristics suggest that