EFFECTS OF INTERFERON ON HUMAN LYMPHOID CELLS AND THEIR FUNCTION
✍ Scribed by I. Heron; M. Hokland; P. Hokland; K. Berg
- Book ID
- 118718200
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- English
- Weight
- 920 KB
- Volume
- 350
- Category
- Article
- ISSN
- 0890-6564
No coin nor oath required. For personal study only.
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## Abstract To investigate the binding of interferon to human lymphoid cells, we purified human α interferon and radio‐labelled it with iodine −125. Binding at 4°C could be saturated and was inhibited by unlabelled interferon; it was specific for cells of human origin. Dissociation constants for th
## Abstract Human leukocyte interferon increased the expression of HLA‐A, B antigens and β~2~‐microglobulin on two lines of human lymphoblastoid cells and on peripheral blood lymphocytes. No effect was observed on the expression of HLA‐DR antigens.